February 2014 Case of the Month

Photomicrographs of a urine sample from a dog

 

Case information

A 6 year old castrated male Akita presented with a one year history of persistent polyuria and polydipsia, that was unresponsive to antibiotic (Amoxicillin) treatment. The dog was difficult to examine, but appeared painful on abdominal palpation. Ultrasonographic imaging showed a diffusely thickened bladder wall. A urine sample was collected by cystocentesis and submitted for urinalysis and cytologic evaluation. Urinalysis results and representative cytologic images (from a cytospin smear of a urine sediment) are provided below.

Urinalysis results
Test Result Units
Volume 2 mL
Color Medium yellow
Turbidity Slightly cloudy
Specific gravity 1.016
pH 8.0 units
Protein 15 (trace) mg/dL
Heme 1+
RBC 5-20 /HPF
WBC <5 /HPF
Bacteria None seen
Epithelial cells Moderate
Sperm None seen

 

Evaluate the representative photomicrographs below and consider the following questions:

  • Interpret the results of the urinalysis.
  • Identify the labeled cells in Figure 1.
  • Is a causative agent evident?
  • what other tests are indicated on the urine?

Figure 1: Cytospin smear from urine sediment  (Wright's stain)
Figure 1: Cytospin smear from urine sediment (Wright’s stain)

Figure 1: Cytospin smear from urine sediment  (Wright's stain)
Figure 1: Cytospin smear from urine sediment (Wright’s stain)

Answer on next page

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