Figure 6. Histologic subtypes of osteosarcomas. A: Osteoblastic, productive type. Note the presence of osteoid and mineralized bone formation (asterix). B: Chondroblastic osteosarcoma. Note light blue chondroid matrix (asterix). C: Fibroblastic type osteosarcoma – the cells are forming long bundles, similar to fibrosarcomas. D: Telangiectatic osteosarcoma. Note the presence of vascular channels (asterix). E: Giant cell type osteosarcoma. Note the presence of multinucleated giant cells (arrow). F: Poorly differentiated osteosarcoma with rare osteoid production (arrow) (H&E stain).
