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…with multiple fluid-filled cavities in the center (corresponding to the liquid center noted on ultrasonographic examination). There were very many (>100) other smaller masses scattered throughout the liver lobes. The duodenal and colonic mucosa and enlarged left kidney were diffusely red (congestion) with hemorrhagic luminal contents in the intestine. Histopathologic examination of hematoxylin-&-eosin-stained sections of formalin-fixed tis…

…fusely coarse liver and a hyperechoic gall bladder wall (inflammation, presumptive). A liver aspirate was taken and submitted to the Animal Health Diagnostic Center at Cornell University for examination. Examine the provided images from the liver aspirate, then answer the following questions: What abnormalities can you identify in the aspirate? What additional tests are indicated? Figure 1: Liver aspirate (Diff-quik, 100x objective) Figu…

…Figure 3a. High power (1000x) image of the mass Figure 4. High power image (500x) of the mass Additional information Figure 5. Histopathologic image of the brain mass Histopathological examination of the surgical biopsy of the brain mass revealed an unencapsulated, highly cellular, infiltrative neoplasm composed of polygonal to spindle-shaped cells arranged in solid sheets and streams on scant fibrous stroma (Figure 5). The cells had indis…

…od of collection explained the hepatocytes found in the sample, and the large swaths of cells initially thought to be smooth muscle were likely the skeletal muscle of the diaphragm. Interestingly, this skeletal muscle is a little divergent from the rest of the skeletal muscle in the body in terms of its innervation and appearance. Additional information on leiomyomas: Smooth muscle tumors are most common in the gastrointestinal and genitourinary…

Joint aspirate from a tortoise Case information: An approximately 18 month old, male Hermann’s tortoise presented for raspy breathing, exuberant, pink tissue over the eyes and being less active than normal. On physical examination the tortoise was small for his age, had increased respiratory rate and effort, was 5% dehydrated and would not open his eyes. While the tortoise was fully ambulatory, his left rear leg was swollen in the tarsal region….