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Quality control material are run daily and monitored over time: The results for the instrument over time is the black line with the red results indicating the mean (red dashed line) and 2SD (+ and -, solid red lines) of all the results compiled from thousands of laboratories using your type of instrument for that test. The green lines indicate the target or expected mean (dashed green line) and 2SD (solid green lines). A: Random bias: The contr…

Please note, that not all possible permeations and combinations are shown in this charts and it should be used as guidelines only. The delta symbol represents the change in the test result (measured result compared to the midpoint of the provided reference interval; for chloride, the corrected chloride should be used in the formulas).

Please note, that not all possible permeations and combinations are shown in this charts and it should be used as guidelines only. The delta symbol represents the change in the test result (measured result compared to the midpoint of the provided reference interval; for chloride, the corrected chloride should be used in the formulas).

Comparison of different hematologic tests between a new method (Y axis) and old method (X axis). The dots represent samples tested with both methods and the black line is the line of best fit (Passing-Bablock regression equation or y = mx + x. A: No bias: With this test, the agreement is good (high correlation or r squared > 0.98) and the line of best fit overlaps with the line of identity, indicating no bias. There is minimal dispersion around…

…either stored in the gall bladder (for those species with a gall bladder) or excreted directly into the small intestine. Within the small intestine, the conjugated bilirubin is degraded by bacterial proteases to urobilinogen, around 10% of which undergoes enterohepatic recirculation after uptake by the portal vein. The “reclaimed” urobilinogen is then freely filtered by the glomerulus and is found in urine (there is a pad for urobilin…

Frequency distribution curve (counts versus test result) of bicarbonate and creatine kinase (CK) results obtained from 124 dogs as part of a reference interval determination study at Cornell University. Bicarbonate results from the dogs show a symmetrical distribution around the mean value, indicating that parametric statistical methods can be used to establish the interval, i.e. mean+/-2SD. The vertical blue lines at either end of both graphs…