Aug 152019

Liver aspirate from a 2 year old cat


Case Information

A 2 year old spayed female domestic longhair cat presented for evaluation of chronic upper respiratory disease. The cat was depressed but not inappetent. Increased activities of alanine aminotransferase (ALT, 966 U/L, reference interval, 28-109 U/L)  and alkaline phosphatase (ALP, 111 U/L, reference interval, 11-49 U/L) were noted on a screening biochemical panel. The cat also had a high total bilirubin concentration (0.7 mg/dL, reference interval, 0-0.1 mg/dL). Abdominal ultrasonographic examination showed a diffusely coarse liver and a hyperechoic gall bladder wall (inflammation, presumptive). A liver aspirate was taken and submitted to the Animal Health Diagnostic Center at Cornell University for examination.

Examine the provided images from the liver aspirate, then answer the following questions:

  1. What abnormalities can you identify in the aspirate?
  2. What additional tests are indicated?

Figure 1: Liver aspirate (Diff-quik, 100x objective)

Figure 2: Liver aspirate (Wright’s stain, 100x objective)

Figure 3: Liver aspirate (Wright’s stain, 100x objective)

Answers on the next page

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