Aspirate from a left axillary mass in an alpaca Case Information An 11-year-old male alpaca was presented to a veterinarian for a mass in the left axilla. The mass had been discovered one year prior during shearing and was approximately 1 x 2 cm and firm on palpation. The mass had grown substantially in the intervening year and was approximately 6 x 6 x 6 cm when examined by the attending veterinarian. No abnormalities were noted in the overlyin…
A macrophage contains phagocytized erythrocytes and pinpoint green-black granules in the cytoplasm (arrow; melanophage and erythrophage). Free melanin granules (arrowhead) are seen in the background with numerous erythrocytes (Wright’s stain, 100x objective)…
Figure 3a: High power image of pleural fluid from a horse with malignant melanoma Read More »
The smear consisted of many non-degenerate neutrophils (arrows) with a few macrophages (circled cell) that contained refractile material, consistent with barium, in the cytoplasm. The same material is seen free in the background (arrowhead). Modified Wright’s stain, 50x objective…
Large numbers of linear M. wenyonii are seen free in the background of the smear. Very few were attached to erythrocytes; this could be an artifact of sample aging. This sample had been mailed to the Clinical Pathology Laboratory and had been 2 days in….
Mycoplasma wenyonii Read More »
Examination of a direct smear of the fluid at low magnification revealed a predominance of macrophages/synoviocytes with lower numbers of eosinophils and small lymphocytes. The background contains a few erythrocytes and free eosinophil granules. The purple and stippled background is a common finding in joint fluid as the fluid contains proteins that yields the characteristic viscosity (e.g. hyaluronic acid) (Wright’s stain, 20x objective)….
Figure 1: Synovial fluid from a horse with left front fetlock lameness Read More »
…with the platelet plug. At the same time, thrombin (by activating thrombin-activatable fibrinolytic inhibitor) and polyphosphates (released from dense granules in platelets) inhibit fibrinolysis , preventing clot breakdown. C: Once the clot forms and the vessel heals, the stimulus for thrombin generation decreases, thrombin begins to inhibit its own production (by binding to thrombomodulin, which activates Protein C; activated Protein C with fre…
Hemostatic pendulum Read More »
Peripheral blood from a cow Case information A 4 year-old Holstein cow was examined due to an acute drop in milk production. The cow freshened two weeks prior to presentation and had initially been producing good quantities of milk. In addition to the acute drop in milk production, the teats in all four quarters were swollen and painful. The swelling decreased with ceftiofur and furosemide therapy, but clinical signs did not fully resolve. Upon…
Figure 1a. Representative image from smears of a bone aspirate from a dog (Wright’s stain, 100x magnification). The smear is of high cellularity and consists of many individual to aggregates of spindle cells with free lipid and low numbers of erythrocytes….
Figure 1a. Bone aspirate from a dog Read More »
Representative high power image of a conjunctival swab from a cat. The arrow is pointing to a perinuclear inclusion consistent with Chlamydia within a conjunctival epithelial cell. The inclusion likely represents a reticulate body (or initial body, see Discussion). The adjacent cell (asterisk) is a heavily pigmented epithelial cell. Free melanin granules are also present throughout the background (arrowheads). Non-degenerate neutrophils are al…
Figure 2a: Eosinophils dominate (with some free eosinophil granules) with low numbers of lightly granulated mast cells (arrow) (Wright’s stain, 50x objective)….
Figure 2a: Tracheal wash from a horse Read More »
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