A higher power image of the non-degenerate neutrophils containing refractile material, consistent with barium (arrows), in the cytoplasm. The same material is free in the background (arrowheads). Modified Wright’s stain, 100x objective…
…ated bilirubin. Hypotheses for fasting-induced hyperbilirubenemia are decreased glucose (decreased conjugation) and competition for uptake by free fatty acids. A mild increasing in total (and unconjugated) bilirubin also occurs in anorexic ruminants (up to 2-3 mg/dL). Figure reproduced with permission from: Hepatic function by Tennant B in “Clinical Biochemistry of Domestic Animals”, 5th edition, Kaneko et al, eds, pg 344, 1997; Copy…
Bilirubin in fasting horses Read More »
…g the spleen, kidney and mesentery. The dog also had a prominent swelling of the third eyelid that was reported to have a mass-like effect. All four of the lesions were aspirated and submitted for cytological evaluation. The splenic aspirate contained components of red and white pulp, with no atypical cells or evidence of inflammation. The aspirate of the mesenteric mass contained free lipid admixed with blood. Photomicrographs of the kidney mass…
…amputated and infected right and left hindlimbs. The dog underwent a complete right hindlimb amputation with no complications. During post-operative care, a urinary catheter was placed and a 4.5cm x 3.4cm x 3.4cm cauliflower mass was observed at the base of the penis. The mass was friable, producing a mild serosanguinous discharge. Impression smears of the mass were taken and submitted to Clinical Pathology for microscopic examination. Evaluate t…
Higher power view of the lungworm larva (arrow) in Figure 2 from this goat. Numerous free larvae were identified in the smear (modified Wright’s stain, 50x objective)….
Figure 4: Sediment of a tracheal wash from goat #2 Read More »
This higher power image demonstrates faint paler stained circular structures in the red blood cells, compatible with small, often called “endogenous”, Heinz bodies. These are barely discernible in the red blood cell (long arrows). The liberated “free” Heinz bodies in the background (arrowheads) are easier to identify. The erythrocyte with the short arrow contains a Howell-jolly body (nuclear fragment, micronucleus) (Wrig…
Figure 5: Representative image of a blood smear from a cyanotic cat with oxidant injury Read More »
The Heinz bodies are more visible at the feathered edge, either “free” in the background (arrowheads) or in ghost cells (arrows), which spread better at the feathered edge and are easier to discern….
Figure 6: Representative image of a blood smear from a cyanotic cat with oxidant injury Read More »
This low power image illustrates storage-associated changes in the leukocytes (neutrophils in this image), with swelling of the nuclear chromatin, forming band-like neutrophils (“pseudo” left shift). Echinocytes also likely reflect ATP depletion in red blood cells with storage. “Free” Heinz bodies are visible from this magnification in the background (arrowheads) (Wright’s stain, 20x objective)….
Figure 4: Representative image of a blood smear from a cyanotic cat with oxidant injury Read More »
…bit, and 3 lions in a different exhibit, also developed a cough, with a lion having a mild decrease in appetite for a few days. The clinical signs in the first tiger persisted for several days, despite symptomatic treatment. To pursue the cause of the cough, the animal was anesthetized and a tracheal wash was performed and submitted to the Cornell University Animal Diagnostic Laboratory for cytologic analysis and testing for infectious diseases….
…to gram negative bacteria. Tissue factor can also be expressed and released by other cells including platelets and eosinophils, but monocytes are thought to be the main source of TF in bacterial sepsis. In cancer, constitutive expression of TF on cancer cells and induction of TF on monocytes by proinflammatory cytokines is the likely trigger of DIC (not shown). Monocyte- or cancer-surface TF, FVIIa, and FXa form an active complex which generates…
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