…association with progression to AML is unclear.6Â These tumors are typically found in skeletal muscle in cattle and the lung, gastrointestinal tract, lymph node, liver or skin in dogs or cats.6Â However, it can arise in any site. Unfortunately, we did not get a direct aspirate of the mediastinal mass for cytologic examination to confirm the possibility of a mediastinal myeloid sarcoma, but we have seen several cases of AML with mediastinal masses…
Aspirate from the gall bladder of a cat Case Information An 11-year-old female spayed domestic shorthair cat was presented with a 3-4 week history of progressive weight loss. The cat was obtained as a kitten from the island of St John and then had lived on a farm in Massachusetts until 8 years of age. The cat had been solely an indoor cat for the prior 3 years with the current owner. Â On examination, the cat was quiet, alert, and responsiv…
…chromocytoma. Measurement of metanephrines in plasma or urine offer the best diagnostic performance and are the tests of first choice for biochemical screening.6 In a study with 7 dogs with pheochromocytoma, a urinary normetanephrine-to-creatinine ratio was significantly increased in dogs with pheochromocytoma compared with dogs with hyperadrenocorticism and healthy dogs.7 In a recent study of 8 dogs with pheochromocytoma, measurement of plasma-f…
…ia? Figure 1: Venous blood from a pancytopenic horse (50x objective) Figure 2: Venous blood from a pancytopenic horse (50x objective) Figure 3: Venous blood from a pancytopenic horse (100x objective) Answers on next page Interpretation Acute leukemia, suspect acute myeloid leukemia, with concurrent myelodysplasia Explanation Examination of a blood smear revealed dysplastic neutrophils (giant forms [Figure 2], hypersegmentation), and…
…4.7 g/dL). The albumin concentration was within the reference interval (2.9 g/dL; RI: 1.9 – 3.2 g/dL). The pancytopenia was characterized by a mild anemia (HCT: 22 %; RI: 30.0 – 47.0 %), leukopenia (3.7 K/μL; RI: 4.9 – 11.1 K/μL) due to a neutropenia (2.4 K/μL; RI: 2.5 – 6.9 K/μL) and moderate thrombocytopenia (49 K/μL; RI: 100 – 250 K/μL). Upon re-examination by the veterinarian, a repeat complete blood count (CBC) was performed and results were…
Lymph node aspirate from a dog  Case Information A 5-year old spayed female mixed breed dog (64 pounds) presented to the oncology service at Cornell University Hospital for Animals for further evaluation of a mass present for roughly one month on the ventral right side of the throat, alongside the trachea. On physical examination, the mass was approximately 7 cm in diameter, firm, and appeared deeply attached and not freely movable. A comp…
…s stain. Figure 3: Peritoneal fluid from a dog, cytospin smear, 100x, Wright’s stain. Using the provided information answer the following questions, What is the predominant cell population in the sample? What is your cytologic diagnosis? What additional test could be considered to further support your diagnosis? Answers on the next page. Footnote a: Mathews, K.A. (2012). ‘Monitoring Fluid Therapy and Complications of Fluid Therapy’, in Di…
…rature of 102.9ºF. The foal was quiet, alert and responsive, but was non-weight bearing on the left pelvic limb and had a moderately sized warm swelling over the left hip with no signs of external trauma. The rest of the physical examination was within normal limits. Blood was drawn for a complete blood count (CBC), equine IgG and serum amyloid A (SAA) testing. The CBC revealed a microcytic normochromic anemia (27% Hct, 34-46%) with a leukocytosi…
…ts provided by the veterinarian showed a severe non-regenerative anemia (Hct = 17%, reference interval, 31-48%) and marked thrombocytopenia (30-50 x 103/µL estimate, reference interval, 195-624 x 103/µL). Neutrophils were within reference intervals (7.1 x 103/µL, reference interval, 2.3-11.6 x 103/µL) but displayed moderate toxic change. Serologic testing was positive for antibodies against feline immunodeficiency virus (FIV), but a feline leukem…
…).4 The presence of copper in biopsies should be qualitatively graded with rhodanine staining because this guides therapy and helps with determination of primary or secondary disease. Copper scores range from 0 (no detection of copper granules) to 5 (panlobular copper distribution). For example, histological grades between 3 (as in this case) and 5 warrant therapy, while treatment may not be recommended for grades below 3.2,4 …
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