Case #2 2026

Peripheral blood and pyloric-duodenal mass aspirate from a cat

 

Case Information

A 15-year-old female spayed Domestic Shorthair cat was admitted as an emergency at the Cornell University Hospital for Animals for severe anemia. The cat had a one week history of hiding and hyporexia with one episode of vomition the day before presentation. On examination, the cat was stable but estimated to be 7% dehydrated. Point-of-care testing showed a severe anemia (packed cell volume, 9%) and hyperlactatemia 3.7 mmol/L (normal, <2 mmol/L). Blood was taken into EDTA- and non-anticoagulant tubes for a hemogram (see results below and Figures 1-2 for morphologic features of the blood cells) and small animal biochemical profile (see results below), respectively, before the cat was given a unit of packed red blood cells. Serum was separated from cells and the serum and EDTA-anticoagulated blood was stored refrigerated before submission to the clinical pathology laboratory the next morning. 

Figure 1: Peripheral blood smear (50x objective)

Figure 2: Peripheral blood smear (100x objective)

The cat was transferred to the Small Animal Medicine Service the next day. A mass effect was palpated in the cranial abdomen. Abdominal ultrosonographic assessment revealed a mass at the pyloric-duodenal junction. A fine-need aspirate was taken of the intestinal mass under ultrasonographic guidance and submitted for cytologic assessment (Figures 3-5). View the images from blood and the intestinal mass and then answer the questions below.

  1. What red blood cell abnormalities are identified in the peripheral blood smear?
  2. What is the likely mechanism for the anemia in this cat?
  3. What is your cytologic diagnosis for the intestinal mass?

 

Figure 3: Intestinal mass (20x objective) 

Figure 4: Intestinal mass (50x objective)

Figure 5: Intestinal mass (100x objective)

Answers on next page

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