Normal neutrophils and neutrophils with toxic change


Normally matured segmented and late band neutrophils, shown in panels A and C, have white cytoplasm with pink granules, long and fairly narrow nuclei and tightly condensed chromatin. Segmented and band neutrophils with toxic change (examples shown in panels B and D) have less condensed chromatin than their normal counterparts and bluer cytoplasm due to retention of ribosomal RNA.