Inflammatory leukogram in a cat


The cat had a moderate leukocytosis (23,000/uL), consisting of a neutrophilia with a left shift (band neutrophils). Neutrophils demonstrated moderate toxic change (cytoplasmic basophilia, cytoplasmic vacuolation, increased Dohle bodies and lighter chromatin than normal). There were platelet clumps and rouleaux formation, the latter indicating increased globulins, likely fibrinogen and immunoglobulins. Results indicated ongoing acute, but not overwhelming, inflammation with a likely bone marrow response (considering the leukocytosis and “regenerative” neutrophilia, with more segmented than band neutrophils). The other leukocyte in this image is a monocyte (modified Wright’s stain).