Neutrophil precursors


This compilation of images is from a cow with severe inflammation secondary to an acute metritis and peritonitis. The cow had a degenerative left shift (more immature than mature neutrophils were counted). These images represent the different stages of neutrophil maturation: A: Mature segmented neutrophil; B: Band neutrophil; C: Neutrophilic metamyelocyte; D: Neutrophilic myelocyte. Note that the immature neutrophils are also demonstrating moderate toxic change – they have cytoplasmic baasophilia and cytoplasmic vacuolation.