December 2015 Case of the Month

Corneal scrape from a mare

Case information

A corneal scrape from a 9 year old mare was submitted to the clinical pathology laboratory for cytologic evaluation. The history provided with the submission detailed a 1.5 week history of a non-healing corneal ulcer. The lesion had been treated by another veterinarian with Neomycin, Polymyxin B, Bacitracin ophthalmic ointment with no improvement. The lesion was approximately 4mm in width, and located under the third eyelid at the corneal limbus. Grossly, the lesion was described as pink in color with raised, granulomatous tissue with visible white granules. The submitting veterinarian assessed the eye as being non-painful.
Representative Wright’s stained images of the corneal scrape are presented below. After examining the images, answer the following questions:

1. What cell types are present?
2. How would you describe the major cell population?
3. What are you differentials for the underlying etiology?

Fig 1 Dec 2015
Figure 1: Corneal scrape (Wright’s stain, 20X)

Figure 2: Corneal scrape (Wright’s stain, 50X)

Figure 3: Corneal scrape (Wright’s stain, 100X)

Figure 1: Corneal scrape (Wright’s stain, 100X)

Answer on next page

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