Acute megakaryoblastic leukemia (AML-M7) in a dog

AML-M7 canine

This dog with pancytopenia (non-regenerative anemia, severe thrombocytopenia, neutropenia) had low numbers of circulating blasts (red arrow) along with dysplastic megakaryocytes (micromegakaryocyte, black arrow) and platelets (arrowhead) (Wright’s stain, 500x magnification). The dog had >20% blasts in bone marrow, many of which were differentiating towards megakaryocytes and showed features of dysplasia. The results confirmed a diagnosis of acute megakaryoblastic leukemia (AML-M7).

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