Bone marrow from a dog with vitamin B6 deficiency and sideroblastic anemia

Bone marrow aspirate from an eight year old Belgian Mallinois with sideroblastic anemia due to vitamin B6 deficiency (same case as previous image): A group of immature nucleated erythroid cells includes a ringed sideroblast (containing >4 blue iron-containing granules and encompassing more than a third of the nuclear circumference, arrow) is present adjacent to another non-ringed sideroblast (lower cell) and non-iron containing erythroid precursor (cell to right). There are also numerous siderocytes (blue-staining iron inclusions in mature red blood cells), Prussian blue stain, 100x objective

Scroll to Top