Chemistry

Minerals

Section outline The major minerals that are measured in chemistry testing are: Calcium (total and free ionized) Phosphate Magnesium Calcium and phosphate homeostasis involves the interrelated actions of the following hormones: Parathyroid hormone (PTH), vitamin D metabolites, and calcitonin. These work their magic on bone, the intestine and kidneys to regulate calcium and phosphate concentrations in […]

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Acid Base

In this section of the site, information will be provided on the following: Overview: Introduction to acid-base and a list of definitions. The different types of acid-base disturbances: Metabolic acidosis, metabolic alkalosis, respiratory acidosis, respiratory alkalosis, and mixed disturbances. We also provide more details on specific acid-base abnormalities, e.g. L- and D-lactic acidosis. Response: How

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Electrolytes

The main electrolytes that are measured in chemistry profiles are: Sodium: The major determinant of effective circulating volume and tonicity. Changes in fluid (loss or gain of fluid) influences sodium concentrations and triggers body responses as outlined in the fluid changes page. Potassium Chloride Because electrolytes are essential to proper functioning of cells, the body

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Techniques

Potentiometry Potentiometry is used to measure electrolytes with ion-specific electrodes. There are two types of potentiometry: direct and indirect. Direct potentiometry: utilized by blood gas machines and does not involve sample dilution. Indirect potentiometry: utilized by automated chemistry analyzers, such as the ones used at Cornell University, and involves sample dilution before analysis. This distinction is

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Iron Metabolism

Section outline Overview: Discussion of the physiology of iron, including iron absorption, transport, recycling, uptake by erythroid progenitors and iron regulation, via the protein hepcidin. Tests related to iron Iron concentrations in blood: How it is measured, interpretation of results. Total iron binding capacity (TIBC): An indirect measure of the iron transport protein, transferrin. How

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Chemistry

Veterinarians use clinical chemistry and other laboratory tests to diagnose disease, to monitor disease progression or response to therapy, and to screen for the presence of underlying disease in apparently healthy animals. A wide variety of clinical chemistry tests are offered by clinical pathology laboratories for this purpose (laboratories differ on the combination of tests

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