Figure 5: Histopathologic section of a biopsy of a mass in the second lumbar vertebra of a cat with paraparesis (CD20 immunostain)

Most of the tumor cells showed strong membrane staining for CD20 (brown stain). This B cell marker can be positive in plasma cell tumors, whereas an immunostain for MUM-1 (typically used as a plasma cell marker) was negative, but we have found this immunostain can be unreliable in cats.

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